NFYA 抗体
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北京 101111
Quick Overview for NFYA 抗体 (ABIN2460199)
抗原
See all NFYA 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is supplied as total IgG.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFYA.
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应用备注
- NFYA antibody can be used for detection of NFYA by ELISA at 1:312500. NFYA antibody can be used for detection of NFYA by western blot at 5.0-8.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFYA antibody at -20 °C.
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- NFYA (Nuclear Transcription Factor Y, alpha (NFYA))
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别名
- NFYA
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背景
- NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
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分子量
- 37 kDa, 34 kDa
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基因ID
- 4800
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NCBI登录号
- NP_002496
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UniProt
- P23511
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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