NFYA 抗体 (C-Term)
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北京 101111
Quick Overview for NFYA 抗体 (C-Term) (ABIN2777243)
抗原
See all NFYA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- NFYA Antibody - C-terminal region
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序列
- YLHESRHRHA MARKRGEGGR FFSPKEKDSP HMQDPNQADE EAMTQIIRVS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%
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产品特性
- This is a rabbit polyclonal antibody against NFYA. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106882
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NFYA (Nuclear Transcription Factor Y, alpha (NFYA))
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别名
- NFYA
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背景
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Targeted Subunit: alpha
Background Information: NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Gene Name: Nuclear transcription factor Y, alpha
Alternative Symbols: HAP2, CBF-A, CBF-B, NF-YA
Protein Name: Nuclear transcription factor Y subunit alpha
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分子量
- 37kDa
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基因ID
- 4800
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NCBI登录号
- NP_002496
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UniProt
- P23511
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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