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RAB8A 抗体

This anti-RAB8A antibody is a 兔 多克隆 antibody detecting RAB8A in WB 和 ELISA. Suitable for 人 和 犬.
产品编号 ABIN2460114
发货至: 中国

Quick Overview for RAB8A 抗体 (ABIN2460114)

抗原

See all RAB8A 抗体
RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

适用

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  • 2
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  • 1
  • 1
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人, 犬

宿主

  • 22
  • 11
  • 3

克隆类型

  • 24
  • 13
多克隆

标记

  • 23
  • 2
  • 2
  • 2
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This RAB8A antibody is un-conjugated

应用范围

  • 20
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  • 1
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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RAB8A.
  • 应用备注

    RAB8A antibody can be used for detection of RAB8A by ELISA at 1:62500. RAB8A antibody can be used for detection of RAB8A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store RAB8A antibody at -20 °C.
  • 抗原

    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

    别名

    RAB8A

    背景

    RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable.The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    分子量

    24 kDa

    基因ID

    4218

    NCBI登录号

    NP_005361

    UniProt

    P61006

    途径

    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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