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PRELP 抗体

PRELP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459967
发货至: 中国
  • 抗原 See all PRELP 抗体
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    适用
    • 29
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    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 17
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    • 2
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    This PRELP antibody is un-conjugated
    应用范围
    • 25
    • 15
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    • 3
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    • 1
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRELP.
    Top Product
    Discover our top product PRELP Primary Antibody
  • 应用备注
    PRELP antibody can be used for detection of PRELP by ELISA at 1:62500. PRELP antibody can be used for detection of PRELP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PRELP antibody at -20 °C.
  • 抗原
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    别名
    PRELP (PRELP 产品)
    别名
    7330409J17Rik antibody, SLRR2A antibody, MST161 antibody, MSTP161 antibody, proline arginine-rich end leucine-rich repeat antibody, proline and arginine rich end leucine rich repeat protein antibody, Prelp antibody, PRELP antibody
    背景
    PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
    分子量
    42 kDa
    基因ID
    5549
    NCBI登录号
    NP_002716
    UniProt
    P51888
    途径
    Glycosaminoglycan Metabolic Process
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