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RHOC 抗体

This anti-RHOC antibody is a 兔 多克隆 antibody detecting RHOC in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠, 犬, Drosophila melanogaster 和 C. elegans.
产品编号 ABIN2459952
发货至: 中国

Quick Overview for RHOC 抗体 (ABIN2459952)

抗原

See all RHOC 抗体
RHOC (Ras Homolog Gene Family, Member C (RHOC))

适用

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人, 小鼠, 大鼠, 犬, Drosophila melanogaster, C. elegans

宿主

  • 31
  • 8

克隆类型

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多克隆

标记

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This RHOC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RHOC.
  • 应用备注

    RHOC antibody can be used for detection of RHOC by ELISA at 1:62500. RHOC antibody can be used for detection of RHOC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store RHOC antibody at -20 °C.
  • 抗原

    RHOC (Ras Homolog Gene Family, Member C (RHOC))

    别名

    RHOC

    背景

    RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    分子量

    22 kDa

    基因ID

    389

    NCBI登录号

    NP_786886

    UniProt

    P08134

    途径

    WNT signaling, Cell-Cell Junction Organization
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