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Klotho beta 抗体

This anti-Klotho beta antibody is a 兔 多克隆 antibody detecting Klotho beta in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2459659
发货至: 中国

Quick Overview for Klotho beta 抗体 (ABIN2459659)

抗原

See all Klotho beta (KLB) 抗体
Klotho beta (KLB)

适用

  • 25
  • 17
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 3
  • 2

克隆类型

  • 33
  • 5
多克隆

标记

  • 25
  • 9
  • 3
  • 1
This Klotho beta antibody is un-conjugated

应用范围

  • 31
  • 25
  • 13
  • 9
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLB.
  • 应用备注

    KLB antibody can be used for detection of KLB by ELISA at 1:12500. KLB antibody can be used for detection of KLB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store KLB antibody at -20 °C.
  • 抗原

    Klotho beta (KLB)

    别名

    KLB

    背景

    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.

    分子量

    120 kDa

    基因ID

    152831

    NCBI登录号

    NP_783864

    UniProt

    Q86Z14

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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