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PCDHA12 抗体

This anti-PCDHA12 antibody is a 兔 多克隆 antibody detecting PCDHA12 in WB 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN2459278
发货至: 中国
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Quick Overview for PCDHA12 抗体 (ABIN2459278)

抗原

See all PCDHA12 抗体
PCDHA12 (Protocadherin alpha 12 (PCDHA12))

适用

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人, 大鼠

宿主

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克隆类型

  • 33
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多克隆

标记

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This PCDHA12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA12.
  • 应用备注

    PCDHA12 antibody can be used for detection of PCDHA12 by ELISA at 1:312500. PCDHA12 antibody can be used for detection of PCDHA12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHA12 antibody at -20 °C.
  • 抗原

    PCDHA12 (Protocadherin alpha 12 (PCDHA12))

    别名

    PCDHA12

    背景

    PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

    分子量

    99 kDa

    基因ID

    56137

    NCBI登录号

    NP_061726

    UniProt

    Q9UN75
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