RMI1 抗体
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Quick Overview for RMI1 抗体 (ABIN2459011)
抗原
See all RMI1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RMI1.
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anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-470) antibody
RMI1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-350) antibodyRMI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 181-443) antibodyRMI1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 1-379) antibodyRMI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) (AA 71-120) antibodyRMI1 适用: 人, 小鼠, 犬, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) antibodyRMI1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- RMI1 antibody can be used for detection of RMI1 by ELISA at 1:1562500. RMI1 antibody can be used for detection of RMI1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RMI1 antibody at -20 °C.
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- RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
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别名
- RMI1
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背景
- RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).
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分子量
- 70 kDa
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基因ID
- 80010
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NCBI登录号
- NP_079221
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UniProt
- Q9H9A7
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途径
- DNA Damage Repair
抗原
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