F13B 抗体
Our Local Distributor
北京 101111
Quick Overview for F13B 抗体 (ABIN2458621)
抗原
See all F13B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Antibody is purified by peptide affinity chromatography method.
-
免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human F13B.
-
-
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 151-179), (N-Term) antibody
F13B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41555 unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (Middle Region) antibodyF13B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (Internal Region) antibodyF13B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (N-Term) antibodyF13B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 21-208) antibodyF13B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 260-403) antibodyF13B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 216-265) antibodyF13B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) antibodyF13B 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (Middle Region) antibodyF13B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor 13, B Polypeptide (F13B) (AA 61-110) antibodyF13B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- F13B antibody can be used for detection of F13B by ELISA at 1:62500. F13B antibody can be used for detection of F13B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store F13B antibody at -20 °C.
-
-
- F13B (Coagulation Factor 13, B Polypeptide (F13B))
-
别名
- F13B
-
背景
- F13B contains 10 Sushi (CCP/SCR) domains. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Defects in F13B can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits, and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
-
分子量
- 73 kDa
-
基因ID
- 2165
-
NCBI登录号
- NP_001985
-
UniProt
- P05160
抗原
-
