SUMO2/3 抗体 (full length)
(1 reference)Quick Overview for SUMO2/3 抗体 (full length) (ABIN2452139)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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特异性
- Specific to SUMO2 and SUMO3 of human, simian, mouse, hamster and rat. Does not react with SUMO1. This antibody recognizes both SUMO2 and SUMO3, but not SUMO1.
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交叉反应 （详细）
- Not tested for other species
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纯化方法
- The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.
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过滤
- Sterile filtered
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免疫原
- Recombinant GST-fused human SUMO3 (full length)
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亚型
- IgG2a kappa
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anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 49-81) antibody
SUMO2/3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84), (C-Term) antibodySUMO2/3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15398 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84) antibodySUMO2/3 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (cleaved), (Gly93) antibodySUMO2/3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 38-64) antibodySUMO2/3 适用: 人 WB 宿主: 兔 Polyclonal RB3377 unconjugated
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应用备注
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1. Western blotting: 1/1,000
2. Immunocytochemistry/Immunofluorescence staining: 1/100~1/500
3. Immunohistochemistry,frozen section: 1/100~1/500
4. ELISA (Assay dependent concentration)
Other applications have not been tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS (x1), 50 % glycerol. Azide and carrier free.
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Upon arrival centrifuge briefly and store at -20 C.
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: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, (2006) (PubMed).
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: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, (2006) (PubMed).
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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别名
- SUMO2/3
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背景
- SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. Unlike ubiquitination, which targets proteins for degradation, SUMO modification plays a critical role in a number of cellular functions including nucleocytoplasmic transport, gene expression, cell cycle and formation of subnuclear structures such as promyelocytic leukemia (PML) bodies. There are three confirmed SUMO isoforms in human, SUMO1, SUMO2 and SUMO3. SUMO2 and 3 show a high degree of similarity to each other and are distinct from SUMO1. Individual SUMO family members are all targeted to different proteins with diverse biological functions. SUMO2/3 forms poly-(SUMO) chains, is conjugated to topoisomerase II and APP, and regulates chromosomal segregation and cellular responses to environmental stress.
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分子量
- 10,871 Da with 95 AA, 11,637 Da with 103 AA
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UniProt
- P61956, P55854
抗原
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