SUMO2/3 抗体
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- 抗原 See all SUMO2/3 products
- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SUMO2/3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- C terminal Human Sumo 2+3
- 克隆位点
- 7G10
- 亚型
- IgG
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anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (full length) antibody
SUMO2/3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC (fro) 宿主: 大鼠 Monoclonal 3H12 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 49-81) antibodySUMO2/3 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84), (C-Term) antibodySUMO2/3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15398 unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 53-84) antibodySUMO2/3 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (cleaved), (Gly93) antibodySUMO2/3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 2/3 (SUMO2/3) (AA 38-64) antibodySUMO2/3 适用: 人 WB 宿主: 兔 Polyclonal RB3377 unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
- 别名
- Sumo 2+3 (SUMO2/3 产品)
- 别名
- SUMO2 antibody, small ubiquitin-like modifier 2 antibody, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)-like antibody, small ubiquitin-related modifier 2 antibody, SUMO2 antibody, LOC711990 antibody, LOC714892 antibody
- 背景
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Synonyms: Small ubiquitin-related modifier 2, HSMT3, SMT3 homolog 2, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3B, Small ubiquitin-related modifier 3, SMT3 homolog 1, SUMO-2, Ubiquitin-like protein SMT3A, SUMO-2, Smt3B, SUMO2, SUMO-3, Smt3A, SUMO3
Background: The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, SUMO-2 and SUMO-3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include IkBa, MDM2, p53, PML and Ran GAP1. SUMO-2 and SUMO-3 contribute to a greater percentage of protein modification than does SUMO-1, and unlike SUMO-1, they can form polymeric chains. In addition, SUMO-3 regulates b-Amyloid generation and may be critical in the onset or progression of Alzheimer's disease.
- UniProt
- P55854, P61956
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