PSMD12 抗体
Quick Overview for PSMD12 抗体 (ABIN2452114)
抗原
See all PSMD12 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn5p
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纯化方法
- Affinity purified
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免疫原
- Recombinant yeast Rpn5p expressed in E. coli
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亚型
- IgG
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应用备注
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1) Western blotting: ~1000 fold dilution
2) Immunoprecipitation Not tested for other applications -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- To avoid repeated freezing and thawing, store the antibody solution in aliquots.
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储存条件
- -20 °C
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The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
: "
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The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
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- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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别名
- Rpn5
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背景
- Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn5p is essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7. It consists of 445 amino acids with molecular weight of 51,768.
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
抗原
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