NUP98 抗体 (AA 1-466)
Quick Overview for NUP98 抗体 (AA 1-466) (ABIN2452066)
抗原
See all NUP98 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-466
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交叉反应 (详细)
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This antibody does not react with Tetrahymena.
Other species have not been tested. -
纯化方法
- Purified
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过滤
- Sterile filtered
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免疫原
- Recombinant GST-fused human Nup98 (aa 1-466)
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亚型
- IgG2c kappa
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应用备注
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1) Western blotting
2) Immunocytochemistry
3) ELISA
4) Dot blotting
Properties:
When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol. Azide- and carrier protein-free.
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Upon arrival centrifuge briefly and store at -20 C.
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: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).
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: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
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- NUP98 (Nucleoporin 98kDa (NUP98))
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别名
- Nup98
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背景
- Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.
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UniProt
- Q9HDC8
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途径
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
抗原
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