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NUP98 抗体 (AA 1-466)

This 大鼠 单克隆 antibody specifically detects NUP98 in WB, ELISA, IF, ICC 和 DB. It exhibits reactivity toward 人, 小鼠, 大鼠, Saccharomyces cerevisiae 和 Schizosaccharomyces pombe. It has been mentioned in 2+ publications
产品编号 ABIN2452066
发货至: 中国
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Quick Overview for NUP98 抗体 (AA 1-466) (ABIN2452066)

抗原

See all NUP98 抗体
NUP98 (Nucleoporin 98kDa (NUP98))

适用

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人, 小鼠, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe

宿主

  • 49
  • 12
大鼠

克隆类型

  • 38
  • 23
单克隆

标记

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This NUP98 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

克隆位点

2H10
  • 抗原表位

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    AA 1-466

    交叉反应 (详细)

    This antibody does not react with Tetrahymena.
    Other species have not been tested.

    纯化方法

    Purified

    过滤

    Sterile filtered

    免疫原

    Recombinant GST-fused human Nup98 (aa 1-466)

    亚型

    IgG2c kappa
  • 应用备注

    1) Western blotting
    2) Immunocytochemistry
    3) ELISA
    4) Dot blotting

    Properties:
    When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol. Azide- and carrier protein-free.

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Upon arrival centrifuge briefly and store at -20 C.
  • Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

    Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).

  • 抗原

    NUP98 (Nucleoporin 98kDa (NUP98))

    别名

    Nup98

    背景

    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.

    UniProt

    Q9HDC8

    途径

    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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