NUP153 抗体 (AA 610-1191)
Quick Overview for NUP153 抗体 (AA 610-1191) (ABIN2452062)
抗原
See all NUP153 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 610-1191
-
特异性
- Specific to human, mouse, rat and monkey Nup153 proteins.
-
交叉反应 (详细)
- Not tested for other species
-
产品特性
- When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.
-
纯化方法
- Purified
-
过滤
- Sterile filtered
-
免疫原
- Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
-
1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.
Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Upon receipt aliquot and store at -20 C
-
-
-
: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).
: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).
-
: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).
-
- NUP153 (Nucleoporin 153kDa (NUP153))
-
别名
- Nup153
-
背景
- The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.
-
UniProt
- P49790
-
途径
- Protein targeting to Nucleus
抗原
-