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FFAR1 抗体 (AA 210-222)

This 兔 多克隆 anti-FFAR1 antibody specifically detects FFAR1 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN2450556
发货至: 中国
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Quick Overview for FFAR1 抗体 (AA 210-222) (ABIN2450556)

抗原

See all FFAR1 抗体
FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

适用

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宿主

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克隆类型

  • 56
多克隆

标记

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This FFAR1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 210-222

    特异性

    GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.

    纯化方法

    Affinity purified

    免疫原

    human GPR40 amino acids 210-222

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    TBS,  pH 7.4, containing 50 % glycerol, 0.5 mg/mL BSA, and 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.
  • 抗原

    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

    别名

    FFAR1 / GPR40

    背景

    Name/Gene ID: FFAR1
    Subfamily: Carboxylic Acid
    Family: GPCR

    Synonyms: FFAR1, FFAR, FFA1R, G protein-coupled receptor 40, GPCR40, GPR40, Free fatty acid receptor, Free fatty acid receptor 1, G-protein coupled receptor 40

    基因ID

    2864

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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