FFAR1 抗体 (AA 210-222)
Quick Overview for FFAR1 抗体 (AA 210-222) (ABIN2450556)
抗原
See all FFAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-222
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特异性
- GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
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纯化方法
- Affinity purified
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免疫原
- human GPR40 amino acids 210-222
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- TBS, pH 7.4, containing 50 % glycerol, 0.5 mg/mL BSA, and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.
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- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
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别名
- FFAR1 / GPR40
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背景
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Name/Gene ID: FFAR1
Subfamily: Carboxylic Acid
Family: GPCR
Synonyms: FFAR1, FFAR, FFA1R, G protein-coupled receptor 40, GPCR40, GPR40, Free fatty acid receptor, Free fatty acid receptor 1, G-protein coupled receptor 40 -
基因ID
- 2864
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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