Integrin beta 7 抗体
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北京 101111
Quick Overview for Integrin beta 7 抗体 (ABIN2433217)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human ITGB7
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亚型
- IgG
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应用备注
- IHC 1:100-1:300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- Avoid freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Integrin beta 7 (ITGB7)
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别名
- ITGB7
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背景
- This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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NCBI登录号
- NP_000880
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途径
- Integrin Complex
抗原
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