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CD24 抗体

CD24 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal SN3 unconjugated
产品编号 ABIN316592
发货至: 中国
  • 抗原 See all CD24 抗体
    CD24 (CD24 Molecule (CD24))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD24 antibody is un-conjugated
    应用范围
    • 85
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    产品特性
    Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen
    纯化方法
    Protein G affinity chromatography.
    免疫原
    Glycoproteins purified from human NALM-1 cell line.
    克隆位点
    SN3
    亚型
    IgG1
    Top Product
    Discover our top product CD24 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry and Immunohistochemistry (frozen sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4 with 15 mM sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    CD24 (CD24 Molecule (CD24))
    别名
    CD24 (CD24 产品)
    别名
    CD24A antibody, Cd24a antibody, CD24 molecule antibody, CD24 antibody, Cd24 antibody
    背景
    CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen
    UniProt
    P25063
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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