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CD24 抗体

This anti-CD24 antibody is a 小鼠 单克隆 antibody detecting CD24 in FACS 和 IHC (fro). Suitable for 人.
产品编号 ABIN238502
发货至: 中国

Quick Overview for CD24 抗体 (ABIN238502)

抗原

See all CD24 抗体
CD24 (CD24 Molecule (CD24))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD24 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

SN3
  • 产品特性

    Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen

    纯化方法

    Protein G affinity chromatography.

    免疫原

    Glycoproteins purified from human NALM-1 cell line.

    亚型

    IgG1
  • 应用备注

    Suitable for Flow Cytometry and Immunohistochemistry (frozen sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.4 with 15 mM sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    CD24 (CD24 Molecule (CD24))

    别名

    CD24

    背景

    CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen

    UniProt

    P25063

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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