HLA-E 抗体
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北京 101111
Quick Overview for HLA-E 抗体 (ABIN238484)
抗原
See all HLA-E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody MEM-E/08 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. The published results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.
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交叉反应 (详细)
- Species reactivity (tested):Human
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产品特性
- Synonyms: HLA-6.2, HLAE, MHC class I antigen E, HLA class I histocompatibility antigen, alpha chain E
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纯化方法
- Protein A-affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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免疫原
- Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide. Remarks: Gene Locus: 6p21. 3
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亚型
- IgG1
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应用备注
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Flow Cytometry. Positive control: human cell line LCL 721.221 (HLA-E transfected). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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背景
- HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.2, HLAE, MHC class I antigen E, alpha chain E
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基因ID
- 3133
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UniProt
- P13747
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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