CD63 抗体 (PE)
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- 抗原 See all CD63 抗体
- CD63
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD63 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody MEM-259 reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Size Exclusion Chromatography
- 免疫原
- HPB-ALL T cell line
- 克隆位点
- MEM-259
- 亚型
- IgG1
- Top Product
- Discover our top product CD63 Primary Antibody
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- 应用备注
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Suitable for Flow Cytometry analysis of human blood cells using 20 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate Buffered Saline (PBS), 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
Shelf Life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CD63
- 别名
- CD63 (CD63 产品)
- 背景
- CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.Synonyms: Granulophysin, ME491, MLA1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, TSPAN30, Tetraspanin-30
- 基因ID
- 967
- UniProt
- P08962
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