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CD21 抗体 (PE)

CR2 适用: 人, Pig, Cow, 犬 FACS 宿主: 小鼠 Monoclonal LT21 PE
产品编号 ABIN238435
发货至: 中国
  • 抗原 See all CD21 (CR2) 抗体
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    适用
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    人, Pig, Cow, 犬
    宿主
    • 83
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD21 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The antibody LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
    产品特性
    Synonyms: Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic CellMarker, Complement C3d receptor, Epstein-Barr virus receptor
    纯化方法
    Size-exclusion chromatography.
    免疫原
    IM9 human B-lymphoblastoid cell line.
    克隆位点
    LT21
    亚型
    IgG1
    Top Product
    Discover our top product CR2 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    别名
    CD21 (CR2 产品)
    别名
    C3DR antibody, CD21 antibody, CR antibody, CVID7 antibody, SLEB9 antibody, Cd21 antibody, cd21 antibody, CR1 antibody, CR1-L antibody, CR2 antibody, complement C3d receptor 2 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, CR2 antibody, Cr2 antibody, CR1 antibody
    背景
    CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
    UniProt
    P20023
    途径
    Complement System
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