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LIME 抗体 (AA 141-295) (PE)

LIME1 适用: 人 FACS 宿主: 小鼠 Monoclonal LIME-06 PE
产品编号 ABIN238427
发货至: 中国
  • 抗原 See all LIME (LIME1) 抗体
    LIME (LIME1) (Lck Interacting Transmembrane Adaptor 1 (LIME1))
    抗原表位
    • 10
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-295
    适用
    • 30
    • 3
    宿主
    • 22
    • 10
    • 1
    小鼠
    克隆类型
    • 24
    • 9
    单克隆
    标记
    • 17
    • 5
    • 3
    • 3
    • 3
    • 2
    This LIME antibody is conjugated to PE
    应用范围
    • 24
    • 16
    • 6
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    特异性
    The antibody LIME-06 was raised against intracellular fragment corresponding to aa 141-295 of human LIME, a 31 kDa Lck-interacting transmembrane adaptor expressed by T cells.
    纯化方法
    Size-exclusion chromatography.
    免疫原
    Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME
    克隆位点
    LIME-06
    亚型
    IgG1
    Top Product
    Discover our top product LIME1 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry analysis (5 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    LIME (LIME1) (Lck Interacting Transmembrane Adaptor 1 (LIME1))
    别名
    LIME1 (LIME1 产品)
    别名
    LIME1 antibody, DKFZp459A158 antibody, LIME antibody, LP8067 antibody, dJ583P15.4 antibody, 2810038K19Rik antibody, RGD1562795 antibody, Lck interacting transmembrane adaptor 1 antibody, LIME1 antibody, Lime1 antibody
    背景
    LIME (Lck-interacting molecule) is a 31 kDa double-palmitoylated protein with unusually basic cytoplasmic domain, expressed by T cells. After ligation of CD4 or CD8 T cell coreceptors, LIME is phosphorylated by Src-family kinases and associates with Lck and Fyn kinases and with their negative regulator Csk. Interestingly, Csk-mediated phosphorylation of C-terminal negative-regulatory tyrosine of LIME-associated Lck can result in increase of enzymatic activity compared with the total pool of Lck, thus, LIME serves as a positive regulator of TCR-dependent T cell signaling. However, under some circumstances, LIME may mediate inhibitory signals.Synonyms: LIME, LIME-1, LIME1, Lck-interacting membrane protein, Lck-interacting molecule, Lck-interacting transmembrane adapter 1
    基因ID
    54923
    UniProt
    Q9H400
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