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Clathrin Heavy Chain (CLTC) (Heavy Chain) 抗体

The 小鼠 单克隆 anti-Clathrin Heavy Chain antibody is suitable to detect Clathrin Heavy Chain in samples from 人, 小鼠, 大鼠, Cow 和 Pig. It has been validated for WB, IF, FACS, IP 和 EIA.
产品编号 ABIN238388
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Clathrin Heavy Chain (CLTC) (Heavy Chain) 抗体 (ABIN238388)

抗原

See all Clathrin Heavy Chain (CLTC) 抗体
Clathrin Heavy Chain (CLTC)

适用

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人, 小鼠, 大鼠, Cow, Pig

宿主

  • 92
  • 31
  • 5
  • 1
小鼠

克隆类型

  • 66
  • 63
单克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

克隆位点

BF-06
  • 抗原表位

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    Heavy Chain

    特异性

    The antibody recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.

    产品特性

    Synonyms: CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain onchromosome 17

    纯化方法

    Ion exchange chromatography

    纯度

    > 95 % (by SDS-PAGE)

    亚型

    IgM
  • 应用备注

    Flow Cytometry: 2-5 μg/mL. Positive control: human blood leukocytes. Immunoprecipitation. Western Blotting. Immunocytochemistry. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. Do not freeze.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Clathrin Heavy Chain (CLTC)

    别名

    Clathrin Heavy Chain

    背景

    Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.Synonyms: CLH17, CLTC, CLTCL2, Clathrin heavy chain on chromosome 17, KIAA0034, Membrane Vesicle Marker

    基因ID

    1213

    UniProt

    Q00610
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