Clathrin Heavy Chain (CLTC) (Heavy Chain) 抗体
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- 抗原 See all Clathrin Heavy Chain (CLTC) 抗体
- Clathrin Heavy Chain (CLTC)
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抗原表位
- Heavy Chain
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适用
- 人, 小鼠, 大鼠, Cow, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- 特异性
- The antibody recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.
- 产品特性
- Synonyms: CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain onchromosome 17
- 纯化方法
- Ion exchange chromatography
- 纯度
- > 95 % (by SDS-PAGE)
- 克隆位点
- BF-06
- 亚型
- IgM
- Top Product
- Discover our top product CLTC Primary Antibody
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- 应用备注
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Flow Cytometry: 2-5 μg/mL. Positive control: human blood leukocytes. Immunoprecipitation. Western Blotting. Immunocytochemistry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody at 2 - 8 °C. Do not freeze.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Clathrin Heavy Chain (CLTC)
- 别名
- Clathrin Heavy Chain (CLTC 产品)
- 背景
- Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.Synonyms: CLH17, CLTC, CLTCL2, Clathrin heavy chain on chromosome 17, KIAA0034, Membrane Vesicle Marker
- 基因ID
- 1213
- UniProt
- Q00610
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