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GDF15 抗体 (N-Term)

This anti-GDF15 antibody is a 小鼠 单克隆 antibody detecting GDF15 in FACS 和 cELISA. Suitable for 人.
产品编号 ABIN238331
发货至: 中国

Quick Overview for GDF15 抗体 (N-Term) (ABIN238331)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 116
  • 41
  • 26
  • 1
  • 1

宿主

  • 107
  • 25
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 104
  • 31
  • 2
单克隆

标记

  • 82
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GDF15 antibody is un-conjugated

应用范围

  • 113
  • 68
  • 62
  • 28
  • 23
  • 14
  • 13
  • 13
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
Flow Cytometry (FACS), Cell-ELISA (cELISA)

克隆位点

ME-6D10
  • 抗原表位

    • 15
    • 12
    • 12
    • 9
    • 7
    • 6
    • 6
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    • 4
    • 2
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    • 2
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    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 30-194, N-Term

    纯化方法

    Protein G

    免疫原

    genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein

    亚型

    IgG1
  • 应用备注

    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.

    说明

    Synonyms: GDF15

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    MIC-1

    背景

    Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.

    UniProt

    Q99988

    途径

    SARS-CoV-2 Protein Interactome
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