FKBP8 抗体 (Internal Region)
Quick Overview for FKBP8 抗体 (Internal Region) (ABIN233735)
抗原
See all FKBP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 200-401-a58
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Supplier
- Rockland
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原理
- FKBP8 Antibody
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交叉反应 （详细）
- This antibody is specific for human FKBP8 protein.
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产品特性
- Synonyms: rabbit anti-FKBP8 Antibody, FKBP 8, FKBP-38, 38 kDa FK 506 binding protein homolog antibody, 38 kDa antibody, FK506 binding protein 8 antibody, FKBP 38 antibody
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纯化方法
- This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human FKBP8 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibody
FKBP8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 58-190) antibodyFKBP8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 60-270) antibodyFKBP8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 93-339) antibodyFKBP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7-2# unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 42-276) antibodyFKBP8 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 1-413) antibodyFKBP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 326-375) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 山羊, 斑马鱼, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-159) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: This protein A purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 64 kDa in size corresponding to FKBP8 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:25,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
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别名
- FKBP8
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背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI). FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP8 may play a role in the regulation of apoptosis. Anti-FKBP8 Antibody is useful for researchers interested in HIV, Cancer, and Metabolism of protein research.
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基因ID
- 23770, 52630440
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UniProt
- Q14318
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途径
- Autophagy
抗原
-
