FKBP8 抗体 (Internal Region)
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- 抗原 See all FKBP8 抗体
- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FKBP8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Supplier Product No.
- 200-401-a58
- Supplier
- Rockland
- 原理
- FKBP8 Antibody
- 交叉反应 （详细）
- This antibody is specific for human FKBP8 protein.
- 产品特性
- Synonyms: rabbit anti-FKBP8 Antibody, FKBP 8, FKBP-38, 38 kDa FK 506 binding protein homolog antibody, 38 kDa antibody, FK506 binding protein 8 antibody, FKBP 38 antibody
- 纯化方法
- This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human FKBP8 protein.
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product FKBP8 Primary Antibody
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anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibody
FKBP8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 58-190) antibodyFKBP8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 60-270) antibodyFKBP8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 93-339) antibodyFKBP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7-2# unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 1-413) antibodyFKBP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-159) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 326-375) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 山羊, 斑马鱼, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 42-276) antibodyFKBP8 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: This protein A purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 64 kDa in size corresponding to FKBP8 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:25,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
- 别名
- FKBP8 (FKBP8 产品)
- 背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI). FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM). Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion, resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol. It has also been suggested that FKBP8 may play a role in the regulation of apoptosis. Anti-FKBP8 Antibody is useful for researchers interested in HIV, Cancer, and Metabolism of protein research.
- 基因ID
- 23770, 52630440
- UniProt
- Q14318
- 途径
- Autophagy
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