KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 476-505 in the C-terminal region of human PKM2, UniProt Accession #NP_002645.
Optimal working conditions should be determined by the investigator.
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
储存液
Without preservative
储存条件
-20 °C
储存方法
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
抗原
PKM2
(Pyruvate Kinase M2 (PKM2))
别名
PKM2
背景
PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.