PKM2 抗体 (Asn491, C-Term) (HRP)
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Quick Overview for PKM2 抗体 (Asn491, C-Term) (HRP) (ABIN2336512)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Asn491, C-Term
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特异性
- Recognizes human PKM2.
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交叉反应
- 人, 小鼠
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交叉反应 (详细)
- Calculated cross reactivity: Hu Mo
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产品特性
- PKM2, CT (N491) (Pyruvate Kinase, Isozymes M1/M2, Pyruvate Kinase Muscle Isozyme, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3) (Azide free) (HRP)
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纯化方法
- Purified by Protein G affinity chromatography.
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免疫原
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 476-505 in the C-terminal region of human PKM2, UniProt Accession #NP_002645.
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亚型
- IgG
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应用备注
- Optimal working conditions should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
- PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
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NCBI登录号
- NP_002645
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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