IRS1 抗体 (pSer612)
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北京 101111
Quick Overview for IRS1 抗体 (pSer612) (ABIN233249)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer612
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特异性
- Detects endogenous IRS-1 only when phosphorylated at serine 612 of mouse IRS-1 or serine 616 of human IRS-1. Does not detect IRS-1 phosphorylated at other sites. Species cross-reactivity: Human. Expected to cross-react with rat based on sequence homology.
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纯化方法
- Immunoaffinity purified
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免疫原
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Synthetic phosphopeptide corresponding to residues surrounding Ser612 of mouse IRS-1 (KLH coupled).
Type of Immunogen: Synthetic phospho-peptide -
亚型
- IgG
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应用备注
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Approved: IP (1:50), WB (1:1000)
Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Immunoprecipitation: 1:50. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
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储存液
- Without preservative
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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别名
- IRS1 / IRS-1
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背景
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Name/Gene ID: IRS1
Synonyms: IRS1, IRS-1, HIRS-1, Insulin receptor substrate 1 -
基因ID
- 3667
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UniProt
- P35568
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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