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CD11b 抗体 (FITC)

This anti-CD11b antibody is a 大鼠 单克隆 antibody detecting CD11b in FACS. Suitable for 人, 小鼠 和 兔.
产品编号 ABIN229754
发货至: 中国

Quick Overview for CD11b 抗体 (FITC) (ABIN229754)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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人, 小鼠, 兔

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD11b antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 特异性

    Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.

    纯化方法

    Protein A purified

    免疫原

    T cell enriched splenocytes from B10 mice.

    Type of Immunogen: Cells

    亚型

    IgG2b
  • 应用备注

    Approved: Flo (1:1 - 1:10)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    ITGAM / CD11b

    背景

    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

    基因ID

    3684

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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