CMA1 抗体
Quick Overview for CMA1 抗体 (ABIN228828)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- May be used to detect mast cells in routinely fixed tissues and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase. Species cross-reactivity: human.
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纯化方法
- Protein G purified
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免疫原
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Purified human skin chymase.
Type of Immunogen: Purified protein -
亚型
- IgG1
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应用备注
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Approved: IHC, IHC-P, WB
Usage: Western Blot1 (Ab 1-2 μg/mL for 2hrs at RT). Immunohistochemistry (Formalin/paraffin) (Use Ab at 0.06-0.12 μg/mL for 30 min at RT). Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 10 mM PBS, pH 7.4.
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- CMA1 / MCT1 / Chymase
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背景
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Name/Gene ID: CMA1
Subfamily: Serine S1
Family: Protease
Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM -
基因ID
- 1215
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UniProt
- P23946
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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