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CMA1 抗体

This anti-CMA1 antibody is a 小鼠 单克隆 antibody detecting CMA1 in WB, IHC 和 IHC (p). Suitable for 人.
产品编号 ABIN228828
发货至: 中国

Quick Overview for CMA1 抗体 (ABIN228828)

抗原

See all CMA1 抗体
CMA1 (Chymase 1, Mast Cell (CMA1))

适用

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宿主

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小鼠

克隆类型

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  • 18
单克隆

标记

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This CMA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    May be used to detect mast cells in routinely fixed tissues and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase. Species cross-reactivity: human.

    纯化方法

    Protein G purified

    免疫原

    Purified human skin chymase.

    Type of Immunogen: Purified protein

    亚型

    IgG1
  • 应用备注

    Approved: IHC, IHC-P, WB

    Usage: Western Blot1 (Ab 1-2 μg/mL for 2hrs at RT). Immunohistochemistry (Formalin/paraffin) (Use Ab at 0.06-0.12 μg/mL for 30 min at RT). Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    10 mM PBS,  pH 7.4.

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    CMA1 (Chymase 1, Mast Cell (CMA1))

    别名

    CMA1 / MCT1 / Chymase

    背景

    Name/Gene ID: CMA1
    Subfamily: Serine S1
    Family: Protease

    Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM

    基因ID

    1215

    UniProt

    P23946

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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