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RAD9A 抗体 (AA 1125-1139)

This 兔 多克隆 anti-RAD9A antibody specifically detects RAD9A in WB 和 ELISA. The antibody is reactive with Saccharomyces cerevisiae samples.
产品编号 ABIN225443
发货至: 中国
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Quick Overview for RAD9A 抗体 (AA 1125-1139) (ABIN225443)

抗原

See all RAD9A 抗体
RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

适用

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Saccharomyces cerevisiae

宿主

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克隆类型

  • 143
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多克隆

标记

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This RAD9A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1125-1139

    特异性

    Detects Saccharomyces cerevisiae Rad9, a protein involved in the DNA damage checkpoint. In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the ortholog of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability. Is pan reactive with both the phosphorylated and non-phosphorylated forms of this protein.

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Hemocyanin (KLH).

    Type of Immunogen: Synthetic peptide - KLH conjugated

    亚型

    IgG
  • 应用备注

    Approved: ELISA (1:2000 - 1:4000), WB (1:50 - 1:250)

    Usage: Western Blot: LS-C42615 detects a band of approximately 60kD.

    说明

    Target Species of Antibody: Yeast

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.2, 0.01 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

    别名

    RAD9A / RAD9

    背景

    Name/Gene ID: RAD9A

    Synonyms: RAD9A, HRAD9, RAD9, RAD9 homolog, RAD9 (S. pombe) homolog, RAD9 homolog A (S. pombe)

    基因ID

    5883

    UniProt

    Q99638

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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