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APC 抗体 (AA 1-433)

This anti-APC antibody is a 小鼠 单克隆 antibody detecting APC in WB, IHC 和 IHC (fro). Suitable for 人.
产品编号 ABIN224804
发货至: 中国

Quick Overview for APC 抗体 (AA 1-433) (ABIN224804)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This APC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 1-433

    特异性

    Recognizes the N-terminal region of the human APC protein. Epitope Mapping: Performed by differential in vitro expression of the N-terminal region of the APC gene by using the protein truncation test. Found to bind to APC in the region between aa135-422 (exon 2-3). Species cross-reactivity: Does not cross-react with mouse.

    纯化方法

    Protein A purified

    免疫原

    Synthetic peptide corresponding to aa1-433 N-terminal fragment of human APC (Adenomatous Polyposis Coli gene Chr 5q) (coupled to maltose binding protein). Cellular localization: cytoplasmic and nuclear.

    Type of Immunogen: Synthetic peptide

    亚型

    IgG1
  • 应用备注

    Approved: IHC, IHC-Fr, WB

    Usage: Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry: Acetone fixed, frozen sections. Positive control: Colon cell line HCT116, SW480 and SW837 extracts.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.2, 40 % glycerol.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    Name/Gene ID: APC

    Synonyms: APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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