APC 抗体 (AA 1-433)
Quick Overview for APC 抗体 (AA 1-433) (ABIN224804)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-433
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特异性
- Recognizes the N-terminal region of the human APC protein. Epitope Mapping: Performed by differential in vitro expression of the N-terminal region of the APC gene by using the protein truncation test. Found to bind to APC in the region between aa135-422 (exon 2-3). Species cross-reactivity: Does not cross-react with mouse.
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纯化方法
- Protein A purified
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免疫原
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Synthetic peptide corresponding to aa1-433 N-terminal fragment of human APC (Adenomatous Polyposis Coli gene Chr 5q) (coupled to maltose binding protein). Cellular localization: cytoplasmic and nuclear.
Type of Immunogen: Synthetic peptide -
亚型
- IgG1
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应用备注
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Approved: IHC, IHC-Fr, WB
Usage: Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry: Acetone fixed, frozen sections. Positive control: Colon cell line HCT116, SW480 and SW837 extracts. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 40 % glycerol.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- APC (Adenomatous Polyposis Coli (APC))
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别名
- APC
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背景
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Name/Gene ID: APC
Synonyms: APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3 -
基因ID
- 324
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UniProt
- P25054
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途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
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