TLR4 抗体
Our Local Distributor
北京 101111
Quick Overview for TLR4 抗体 (ABIN2192090)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
过滤
- 0.2 μm filtered
-
免疫原
- CHO cells expressing chimeric human TLR4/MD-2 fusion protein
-
-
anti-Toll-Like Receptor 4 (TLR4) (AA 751-835) antibody
TLR4 适用: 人, 小鼠, 大鼠, Cow WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibodyTLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 49-247) antibodyTLR4 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (HRP)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal HRP
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (FITC)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal FITC
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Biotin)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal Biotin
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (PE)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal PE
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (APC)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal APC
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (PerCP)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal PerCP
anti-Toll-Like Receptor 4 (TLR4) (AA 420-435) antibody (Atto 488)TLR4 适用: 人 WB, FACS, IHC, ICC, IF 宿主: 兔 Polyclonal Atto 488
-
-
应用备注
- For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS, containing 0.1 % bovine serum albumin.
-
储存条件
- 4 °C
-
储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
-
有效期
- 12 months
-
-
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
别名
- Toll-Like Receptor 4
-
背景
- The monoclonal antibody 3C3 reacts with human Toll-like receptor 4 (TLR4, CD284). TLRs belong to a family of proteins that specifically recognize and sense microbial products. They are highly conserved throughout evolution. In Drosophila, toll is required for the anti-fungal response, while the related 18- wheeler is involved in antibacterial defences. TLRs identified as type I transmembrane signalling receptors act as innate immune recognition receptors against many pathogens. TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to LPS of Gram- negative bacteria. The monoclonal antibody 3C3 is a TLR4 function-blocking antibody that is useful for studies on the role of TLR4 as a receptor for LPS induced cytokine production by TLR4 bearing cells.
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
-
