ELANE 抗体
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- 抗原 See all ELANE 抗体
- ELANE (Elastase, Neutrophil Expressed (ELANE))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ELANE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoassay (IA)
- 过滤
- 0.2 μm filtered
- 克隆位点
- 265-3K1
- Top Product
- Discover our top product ELANE Primary Antibody
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anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibody
ELANE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6B10 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-247) antibodyELANE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 140-267) antibodyELANE 适用: 人, 大鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6B6G6 unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 101-200) antibodyELANE 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 30-267) antibodyELANE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC, FACS 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Elastase, Neutrophil Expressed (ELANE) antibodyELANE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Elastase, Neutrophil Expressed (ELANE) (AA 168-267) antibodyELANE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
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- 应用备注
- For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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- 抗原
- ELANE (Elastase, Neutrophil Expressed (ELANE))
- 别名
- Leukocyte Elastase (ELANE 产品)
- 别名
- ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, Ela2 antibody, F430011M15Rik antibody, ela2 antibody, ELANE antibody, elastase, neutrophil expressed antibody, proteinase 3 antibody, ELANE antibody, Elane antibody, prtn3 antibody
- 背景
- The monoclonal antibody 265-3K1 recognizes human leukocyte elastase. Leukocyte elastase, a major serine proteinase in man, is predominantly present in the azurophilic granules of neutrophils and monocytes. Elastase has a broad range of extracellular matrix substrates including elastin, proteoglycans, collagen and fibronectin. The action of elastase is controlled by serine proteinase inhibitors. Elastase, when released during inflammation, is rapidly bound by its two main inhibitors, alpha1-PI and alpha2-macroglobuline to form elastase-inhibitor complexes. In addition mucosa secretions may contain the locally secreted elastase inhibitors elafin/SKALP and SLPI. When secreted at sites of inflammation elastase can cause severe tissue damage. An important role has been suggested for human elastase in various inflammatory disorders, including pulmonary emphysema, sepsis, arthritis, nephritis and certain skin diseases. Elastase induces the production of IL-8 in human bronchial epithelial, a proces that occurs in part through TLR4.
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