Ficolin 2 抗体
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北京 101111
Quick Overview for Ficolin 2 抗体 (ABIN2191965)
抗原
See all Ficolin 2 (FCN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Cross reactivity: Rat : Yes
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过滤
- 0.2 μm filtered
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亚型
- IgG1
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anti-Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2) (AA 1-313) antibody
FCN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2) (AA 97-254) antibodyFCN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2) (AA 230-290) antibodyFCN2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2) (AA 1-313) antibodyFCN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- For immunohistochemistry, immunoprecipitation and immuno assays, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
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限制
- 仅限研究用
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缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
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: "Activation of the lectin complement pathway by H-ficolin (Hakata antigen)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3502-6, (2002) (PubMed).
: "Activation of the lectin complement pathway by ficolins." in: International immunopharmacology, Vol. 1, Issue 3, pp. 359-63, (2001) (PubMed).
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: "Activation of the lectin complement pathway by H-ficolin (Hakata antigen)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3502-6, (2002) (PubMed).
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- Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))
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别名
- Ficolin-2
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背景
- The monoclonal antibody GN4 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation. Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2 - MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity. Aliases Ficolin-2/P35, L-ficolin, ficolin L, EBP-37 or hucolin
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途径
- Complement System
抗原
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