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Interferon gamma 抗体

IFNG 适用: 人 IP, Neut, IHC (fro), IA 宿主: 小鼠 Monoclonal F12 unconjugated
产品编号 ABIN2191865
发货至: 中国
  • 抗原 See all Interferon gamma (IFNG) 抗体
    Interferon gamma (IFNG)
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    小鼠
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    单克隆
    标记
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    This Interferon gamma antibody is un-conjugated
    应用范围
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    Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)
    克隆位点
    F12
    Top Product
    Discover our top product IFNG Primary Antibody
  • 应用备注
    For immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity in vitro dilutions have to be made according to the amount of IFN-gamma to be inactivated. One neutralizing unit of anti-human gamma interferon is defined as the amount of antibody sufficient for neutralizing one unit human gamma interferon (ref.: NIH standard Gg23- 901-530).
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute the vial by injection of 1 mLdistilled or de-ionized water (Caution: vial is under vacuum).
    缓冲液
    Lyophilized product in PBS, containing 300 μg antibody.
    注意事项
    Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.
    储存条件
    4 °C
    储存方法
    Lyophilized product should be stored at 4 °C Store stock solution in aliquots at -20 °C Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Billiau: "Gamma-interferon: the match that lights the fire?" in: Immunology today, Vol. 9, Issue 2, pp. 37-40, (1989) (PubMed).

    Jacob, van der Meide, McDevitt: "In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon." in: The Journal of experimental medicine, Vol. 166, Issue 3, pp. 798-803, (1987) (PubMed).

    Van der Meide, Dubbeld, Schellekens: "Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA." in: Journal of immunological methods, Vol. 79, Issue 2, pp. 293-305, (1985) (PubMed).

    Armstrong: "Semi-micro, dye-binding assay for rabbit interferon." in: Applied microbiology, Vol. 21, Issue 4, pp. 723-5, (1971) (PubMed).

  • 抗原
    Interferon gamma (IFNG)
    别名
    gamma Interferon (IFNG 产品)
    别名
    IFG antibody, IFI antibody, IFN-g antibody, Ifg antibody, IFNG2 antibody, IFN-gamma antibody, IFN-G antibody, IFNG antibody, IFNgamma antibody, TCRalpha antibody, INF-G antibody, ifng antibody, interferon gamma antibody, interferon, gamma 1-2 antibody, IFNG antibody, Ifng antibody, ifng1-2 antibody
    背景
    Monoclonal antibody binds and neutralizes both natural and recombinant human gamma Interferon. Cross reactivity with other cytokines has not been found. The antibody does not react with rodent interferons. Possible applications include the purification of human gamma Interferon and in vitro neutralisation. In general, monoclonal antibodies to gamma Interferon are able to inhibit Schwartzman reactions and in the murine system appear to protect NZB mice against spontaneous development of autoimmune disease.
    途径
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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