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CD46 抗体

CD46 适用: 小鼠 WB, FACS, IF, IHC (fro), IA 宿主: 大鼠 Monoclonal MM10 unconjugated
产品编号 ABIN2191857
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 118
    • 38
    • 20
    • 10
    • 10
    • 1
    小鼠
    宿主
    • 85
    • 53
    • 1
    大鼠
    克隆类型
    • 73
    • 66
    单克隆
    标记
    • 52
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    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
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    This CD46 antibody is un-conjugated
    应用范围
    • 91
    • 79
    • 42
    • 40
    • 33
    • 19
    • 14
    • 14
    • 14
    • 10
    • 6
    • 5
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)
    交叉反应 (详细)
    Cross reactivity: Rat CD46 : Yes
    过滤
    0.2 μm filtered
    克隆位点
    MM10
    亚型
    IgG2a
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    For immune histology, flow cytometry and western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilution. The typical starting working dilution is 1:50. IA: Rat CD46 or mouse CD46 variant as coating on a micro titer plate Positive control
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Frolikova, Otcenaskova, Valasková, Postlerova, Stopkova, Stopka, Komrskova: "The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).

  • 抗原
    CD46
    别名
    Membrane Cofactor Protein (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    背景
    The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria. Aliases MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor Immunogen Mouse CD46-human Fc fusion protein
    途径
    Regulation of Actin Filament Polymerization
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