PVRL2 抗体
(2 references)Quick Overview for PVRL2 抗体 (ABIN2191800)
抗原
See all PVRL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 76-353) antibody
PVRL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A6-2C1 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 58-212) antibodyPVRL2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4A11B12 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 251-350) antibodyPVRL2 适用: 人 WB, FACS, ELISA, ICC, IF (p), IHC (fro), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 83-291) antibodyPVRL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) antibodyPVRL2 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal R2-525 unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) antibody (PE)PVRL2 适用: 人 FACS 宿主: 小鼠 Monoclonal R2-525 PE
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) (AA 1-479) antibodyPVRL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2) antibodyPVRL2 适用: 人 FACS, ELISA, IP 宿主: 小鼠 Monoclonal B-C12 unconjugated
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应用备注
- For flow cytometry, Western blotting and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended.
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限制
- 仅限研究用
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缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
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有效期
- 12 months
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: "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48350-5, (2001) (PubMed).
: "Different behavior of l-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction." in: Oncogene, Vol. 18, Issue 8, pp. 1609-17, (1999) (PubMed).
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: "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48350-5, (2001) (PubMed).
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- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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别名
- Nectin-2
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背景
- Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse nectin-2. The antibody cross reacts with human nectin-2.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
抗原
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