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LY86 抗体

This anti-LY86 antibody is a 大鼠 单克隆 antibody detecting LY86 in FACS 和 Func. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2191781
发货至: 中国

Quick Overview for LY86 抗体 (ABIN2191781)

抗原

See all LY86 抗体
LY86 (Lymphocyte Antigen 86 (LY86))

适用

  • 28
  • 17
  • 17
小鼠

宿主

  • 39
  • 5
  • 4
大鼠

克隆类型

  • 41
  • 7
单克隆

标记

  • 22
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LY86 antibody is un-conjugated

应用范围

  • 37
  • 14
  • 13
  • 13
  • 10
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

MD113
  • 过滤

    0.2 μm filtered
  • 应用备注

    For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

    有效期

    12 months
  • Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: "Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide." in: Blood, Vol. 99, Issue 5, pp. 1699-705, (2002) (PubMed).

  • 抗原

    LY86 (Lymphocyte Antigen 86 (LY86))

    别名

    Md-1

    背景

    The monoclonal antibody MD113 reacts with mouse MD-1. MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS. The MD113 antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.

    途径

    Toll-Like Receptors Cascades
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