CCL2 抗体
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北京 101111
Quick Overview for CCL2 抗体 (ABIN2191758)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Cross reactivity: Human : No
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过滤
- 0.2 μm filtered
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亚型
- IgG1
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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibody
CCL2 适用: 人, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 61-148) antibodyCCL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人 WB, IHC, ELISA, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96) antibodyCCL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89), (C-Term) antibodyCCL2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB17838 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人, 小鼠, 猴 WB, IHC (p), IF, FACS, EIA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibodyCCL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- For immunohistochemistry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
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限制
- 仅限研究用
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缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
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: "An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3637-51, (2009) (PubMed).
: "Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism." in: European journal of pharmacology, Vol. 584, Issue 2-3, pp. 415-23, (2008) (PubMed).
: "Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice." in: Journal of the American Society of Nephrology : JASN, Vol. 8, Issue 5, pp. 720-9, (1997) (PubMed).
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: "An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3637-51, (2009) (PubMed).
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- Monocyte Chemoattractant Protein 1
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背景
- The monoclonal antibody ECE.2 recognizes mouse monocyte chemoattractant protein 1 (MCP-1). The murine JE gene encodes the monocyte-specific cytokine monocyte chemotactic protein 1 (MCP- 1). MCP-1 is a CC chemokine of 76 amino acids (~11 kDa) and is chemotactic for monocytes and basophils but not neutrophils and eosinophils. MCP-1 is expressed by smooth muscle cells (SMC), macrophages, endothelial cells, keratinocytes and fibroblasts in response to inflammatory stimuli such as interleukin 1β and tumor necrosis factor α. MCP-1 has been implicated in a variety of inflammatory processes, including inflammatory bowel disease, rheumatoid arthritis, asthma, nephritis, and parasitic and viral infections. MCP-1 antigen is not detected in the endothelium or SMC of normal arteries. MCP-1 has also been shown to exhibit biological activities other than chemotaxis. It can induce the proliferation and activation of killer cells known as CHAK (CC-Chemokine-activated killer) MCP-1 signals via the CCR2 receptor, and is critical for aneurysm formation because of its
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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