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Interferon gamma 抗体

This anti-Interferon gamma antibody is a 大鼠 单克隆 antibody detecting Interferon gamma in IP, IA 和 Purif. Suitable for 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN2191745
发货至: 中国

Quick Overview for Interferon gamma 抗体 (ABIN2191745)

抗原

See all Interferon gamma (IFNG) 抗体
Interferon gamma (IFNG)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Interferon gamma antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunoassay (IA), Purification (Purif)

克隆位点

F1
  • 过滤

    0.2 μm filtered
  • 应用备注

    The antibody can be used for the purification or immunochemical investigation of mouse gamma Interferon and structural studies. Furthermore the antibody is useful for immunoprecipitation and as a tracer antibody in immuno assay procedures.

    限制

    仅限研究用
  • 缓冲液

    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.

    储存条件

    4 °C

    储存方法

    Product should be stored at 4 °C. Store stock solution in aliquots at -20°C. Repeated freeze and thaw cycles will cause loss of activity. Under recommended storage conditions, product is stable for one year.

    有效期

    12 months
  • Billiau, Heremans, Vandekerckhove, Dillen: "Anti-interferon-gamma antibody protects mice against the generalized Shwartzman reaction." in: European journal of immunology, Vol. 17, Issue 12, pp. 1851-4, (1988) (PubMed).

    Dijkmans, Heremans, Billiau: "Heterogeneity of Chinese hamster ovary cell-produced recombinant murine interferon-gamma." in: The Journal of biological chemistry, Vol. 262, Issue 6, pp. 2528-35, (1987) (PubMed).

    Heremans, Dijkmans, Sobis, Vandekerckhove, Billiau: "Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 12, pp. 4175-9, (1987) (PubMed).

    Jacob, van der Meide, McDevitt: "In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon." in: The Journal of experimental medicine, Vol. 166, Issue 3, pp. 798-803, (1987) (PubMed).

    van Tiel, Boere, Vinjé, Harmsen, Benaissa-Trouw, Kraaijeveld, Snippe: "Detection of Semliki Forest virus in cell culture by use of an enzyme immunoassay with peroxidase-labeled monoclonal antibodies specific for glycoproteins E1 and E2." in: Journal of clinical microbiology, Vol. 20, Issue 3, pp. 387-90, (1984) (PubMed).

  • 抗原

    Interferon gamma (IFNG)

    别名

    gamma Interferon

    背景

    Monoclonal antibody F1 binds both natural and recombinant mouse gamma Interferon. Its binding activity has been demonstrated in vitro and in vivo. F1 antibodies have been demonstrated to be able to inhibit inflammatory responses to bacterial lipopolysaccharides. These antibodies were furthermore shown to inhibit Shwartzman reactions and to protect NZB mice against spontaneous development of autoimmune disease. The neutralizing activity of the antibody has been demonstrated as being poor in anti-viral assays. If a neutralizing antibody is specifically desired, we recommend the use of another antibody available from Hycult Biotech, namely F3 (prod. code HM1005) which recognizes a different epitope on the murine gamma Interferon molecule and in contrast to F1, exhibits strong neutralizing activity. The antibody does not react with rat or human gamma interferon.

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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