Superoxide dismutase copper chaperone 抗体 (AA 201-274)
Quick Overview for Superoxide dismutase copper chaperone 抗体 (AA 201-274) (ABIN2179351)
抗原
See all Superoxide dismutase copper chaperone (CCS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-274
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预测反应
- Human,Mouse,Rat,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SOD4
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亚型
- IgG
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anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 175-274) antibody
CCS 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 23-269) antibodyCCS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (C-Term) antibodyCCS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) antibodyCCS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 1-274) antibodyCCS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 27-268) antibodyCCS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 27-268) antibodyCCS 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 23-269) antibodyCCS 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (C-Term) antibodyCCS 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Copper Chaperone For Superoxide Dismutase (CCS) (AA 145-274) antibodyCCS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))
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别名
- SOD4/CCS
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背景
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Synonyms: CCS, CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone.
Background: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
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基因ID
- 9973
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途径
- Transition Metal Ion Homeostasis
抗原
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