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SLK 抗体 (pTyr530) (AbBy Fluor® 647)

This anti-SLK antibody is a 兔 多克隆 antibody detecting SLK in IF (cc) 和 IF (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN2179279
发货至: 中国

Quick Overview for SLK 抗体 (pTyr530) (AbBy Fluor® 647) (ABIN2179279)

抗原

See all SLK 抗体
SLK (STE20-Like Kinase (SLK))

适用

  • 53
  • 42
  • 25
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 66
  • 1

克隆类型

  • 66
  • 1
多克隆

标记

  • 18
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SLK antibody is conjugated to AbBy Fluor® 647

应用范围

  • 44
  • 38
  • 38
  • 16
  • 11
  • 9
  • 8
  • 7
  • 4
  • 4
  • 3
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 15
    • 14
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr530

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SLK (STE20-Like Kinase (SLK))

    别名

    SLK

    背景

    Synonyms: Fyn phospho Y530, p-Fyn phospho Y530, C syn protooncogene, FYN oncogene related to SRC FGR YES_ MGC45350_ OKT3 induced calcium influx regulator_ P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, Src like kinase, Src yes related novel gene, Src/yes related novel gene, SYN, FYN, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT.

    Background: Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1. The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.

    基因ID

    2534
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