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SLK 抗体 (pTyr530)

SLK 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2179275
发货至: 中国
  • 抗原 See all SLK 抗体
    SLK (STE20-Like Kinase (SLK))
    抗原表位
    • 15
    • 15
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pTyr530
    适用
    • 45
    • 35
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 58
    • 1
    克隆类型
    • 58
    • 1
    多克隆
    标记
    • 16
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This SLK antibody is un-conjugated
    应用范围
    • 42
    • 38
    • 38
    • 14
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530
    亚型
    IgG
    Top Product
    Discover our top product SLK Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SLK (STE20-Like Kinase (SLK))
    别名
    SLK (SLK 产品)
    别名
    BcDNA:LD05623 antibody, CG40293 antibody, Dmel\\CG40293 antibody, LD05623 antibody, LOSK antibody, STK2 antibody, bA16H23.1 antibody, se20-9 antibody, 9A2 antibody, AV021402 antibody, AW411554 antibody, Etk4 antibody, SMAK antibody, Stk2 antibody, mKIAA0204 antibody, mSLK antibody, STE20 like kinase antibody, Ste20-like kinase antibody, STE20-like kinase antibody, SLK antibody, Stlk antibody, Slk antibody
    背景

    Synonyms: Fyn phospho Y530, p-Fyn phospho Y530, C syn protooncogene, FYN oncogene related to SRC FGR YES_ MGC45350_ OKT3 induced calcium influx regulator_ P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, Src like kinase, Src yes related novel gene, Src/yes related novel gene, SYN, FYN, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT.

    Background: Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1. The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.

    基因ID
    2534
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