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RAD17 抗体 (PE)

The PE-conjugated 兔 多克隆 anti-RAD17 antibody (ABIN2178768) specifically detects RAD17 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2178768
发货至: 中国
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Room 801-803
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Quick Overview for RAD17 抗体 (PE) (ABIN2178768)

抗原

See all RAD17 抗体
RAD17

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 103
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多克隆

标记

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This RAD17 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Rad17

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4 °C for 12 months.
  • 抗原

    RAD17

    别名

    Rad17

    背景

    The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013].
    Synonyms: RFC, CCYC, Cell cycle checkpoint protein, Cell cycle checkpoint protein RAD17, HRAD 17, hRad17, R24L, Rad 17, Rad 24, RAD1 S. pombe homolog, RAD17, RAD17 homolog, Rad17 like protein, RAD17_HUMAN, RAD17Sp, Rad24, RF C activator 1 homolog, RF C/activator 1 homolog, RF-C/activator 1 homolog.

    基因ID

    5884
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