BAFF 抗体
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北京 101111
Quick Overview for BAFF 抗体 (ABIN217771)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes CD257 (otherwise known as BAFF/BLyS), a 285 amino acid type II transmembrane protein and member of the tumor necrosis factor (TNF) superfamily of ligands, which acts as a B and T cell stimulator and plays a role in the development of autoimmune diseases such as systemic lupus erythematosus. CD257 is expressed by monocytes, macrophages, T cells and dendritic cells and acts through binding to CD267 (TACI), CD269 (BCMA) and CD268 (BAFFR) receptors, the latter interaction playing a critical role in the activation, survival, differentiation and proliferation of B cells.
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纯化方法
- Protein A purified
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免疫原
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Recombinant human CD257.
Type of Immunogen: Recombinant protein -
亚型
- IgG1
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应用备注
- Approved: ELISA (5 - 6 μg/mL)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Distilled Water.
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浓度
- Lot specific
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缓冲液
- Lyophilized, PBS, pH 7.2.
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- BAFF
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背景
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Name/Gene ID: TNFSF13B
Family: TNF
Synonyms: TNFSF13B, B-cell-activating factor, BAFF, ApoL related ligand TALL-1, B-lymphocyte stimulator, CD257, BLYS, Delta4 BAFF, Delta BAFF, TALL-1, TALL1, ZTNF4, THANK, B lymphocyte stimulator, CD257 antigen, TNFSF20 -
基因ID
- 10673
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UniProt
- Q9Y275
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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