LRP5 抗体 (AA 500-550) (PE)
Quick Overview for LRP5 抗体 (AA 500-550) (PE) (ABIN2177409)
抗原
See all LRP5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 500-550
-
特异性
- This antibody will recognize LRP6 due to high sequence similarity.
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human LRP5
-
亚型
- IgG
-
-
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1000-1250) antibody
LRP5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (Internal Region) antibodyVerified LRP5 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 451-550) antibodyLRP5 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 769-1016) antibodyLRP5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 41-130) antibodyLRP5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 1538-1567) antibodyLRP5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) antibodyLRP5 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 501-600) antibodyLRP5 适用: 小鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 102-336) antibodyLRP5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
说明
-
Exitation/Emission: 480,565nm/578nm
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at 4°C
-
有效期
- 12 months
-
-
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
-
别名
- Lrp5
-
背景
-
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.
Subcellular location: Extracellular
Synonyms: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, LRP-5, OPTA1, VBCH2, Low-density lipoprotein receptor-related protein 5, LRP5 -
基因ID
- 4041
-
UniProt
- O75197
-
途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
抗原
-
