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KDM5A 抗体 (AA 101-200) (AbBy Fluor® 350)

This anti-KDM5A antibody is a 兔 多克隆 antibody detecting KDM5A in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN2177122
发货至: 中国

Quick Overview for KDM5A 抗体 (AA 101-200) (AbBy Fluor® 350) (ABIN2177122)

抗原

See all KDM5A 抗体
KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

适用

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宿主

  • 55
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克隆类型

  • 48
  • 13
多克隆

标记

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This KDM5A antibody is conjugated to AbBy Fluor® 350

应用范围

  • 40
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    AA 101-200

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human KDM5A

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

    别名

    KDM5A

    背景

    Synonyms: RBP2, RBBP2, RBBP-2, Lysine-specific demethylase 5A, Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Retinoblastoma-binding protein 2, KDM5A, JARID1A

    Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity).

    基因ID

    5927

    UniProt

    P29375

    途径

    Chromatin Binding, Warburg Effect
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