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FAM48A/P38IP 抗体 (AA 21-120) (HRP)

This anti-FAM48A/P38IP antibody is a 兔 多克隆 antibody detecting FAM48A/P38IP in ELISA, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN2174057
发货至: 中国

Quick Overview for FAM48A/P38IP 抗体 (AA 21-120) (HRP) (ABIN2174057)

抗原

See all FAM48A/P38IP (SUPT20H) 抗体
FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))

适用

  • 20
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宿主

  • 20

克隆类型

  • 20
多克隆

标记

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This FAM48A/P38IP antibody is conjugated to HRP

应用范围

  • 13
  • 13
  • 5
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  • 2
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ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
    • 3
    • 1
    • 1
    AA 21-120

    预测反应

    Human,Mouse,Rat,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human FAM48A

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))

    别名

    FAM48A

    背景

    Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

    Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

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