CTNNA3 抗体 (AA 131-230) (HRP)
Quick Overview for CTNNA3 抗体 (AA 131-230) (HRP) (ABIN2173441)
抗原
See all CTNNA3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 131-230
-
预测反应
- Human,Mouse,Rat,Dog,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CTNNA3
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))
-
别名
- CTNNA3
-
背景
-
Synonyms: 4930429L08Rik, 4933408A16, Alpha catenin like protein, Alpha T catenin, Alpha T-catenin, Cadherin associated protein, Cadherin-associated protein, Catenin alpha 3, Catenin alpha-3, Catna3, CTNA3_HUMAN, CTNNA3, MGC26194, MGC75041, OTTHUMP00000019684, OTTMUSP00000028119, OTTMUSP00000028120, RP11-433J16.1, VR22.
Background: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
抗原
-