GJB2 抗体 (Cytoplasmic Domain)
Quick Overview for GJB2 抗体 (Cytoplasmic Domain) (ABIN215079)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cytoplasmic Domain
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特异性
- Reacts predominantly with Connexin 26. By immunoblot analysis, a 26kD protein from mouse liver membrane, mouse brain extract and rat brain extract was detected (note: samples were not boiled prior to running SDS-PAGE). A few cross-reactive bands were detected in the 45-50kD range. The identity of these proteins has yet to be confirmed, however, it is possible these bands represent dimeric forms of the Connexin 26 protein. Immunohistochemical staining of frozen sections of human cochlea showed positive reactivity for Connexin 26.
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纯化方法
- Immunoaffinity purified
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免疫原
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Peptide corresponding to a portion of the cytoplasmic loop of rat connexin 26.
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: ELISA, IF, IHC, IHC-Fr, WB
Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. ELISA: 0.1-1.0 mg/mL. Western Blot: 0.5 mg/mL. Immunohistochemistry (frozen): 10 mg/mL. Immunofluorescence. -
说明
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Target Species of Antibody: Rat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
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别名
- GJB2 / CX26 / Connexin 26
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背景
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Name/Gene ID: GJB2
Subfamily: Connexin
Family: Ion Channel
Synonyms: GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A -
基因ID
- 2706
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UniProt
- P29033
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途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
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